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Details Ibuprofen (Generic Advil) Generic Name: Ibuprofen Strips of 10 x 400mg Capsules Manufactured by Knoll Pharmaceuticals Use Ibuprofen is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis and gout. It isalso used to reduce fever and to relieve headaches, muscle aches, menstrual pain, aches and pains from the common cold, backache, and pain after surgery or dental work. Dosage For minor aches, mild to moderate pain, menstrual cramps and fever the usual adult dose is 200 or 400 mg every 4 to 6 hours. Arthritis is treated with 300 to 800 mg 3 or 4 times daily. When under the care of a physician, the maximum dose of ibuprofen is 3.2 g daily. Otherwise, the maximum dose is 1.2 g daily. Individuals should not use ibuprofen for more than 10 days for the treatment of pain or more than 3 days for the treatment of a fever unless directed by a physician. Side Effects Although side effects from ibuprofen are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away: headache, dizziness, nervousness, upset stomach, stomach pain or cramps, vomiting, constipation, diarrhea, gas. If you experience any of the following symptoms, call your doctor immediately: bloody vomit, bloody diarrhea or black, tarry stools, ringing in the ears, blurred vision, swelling of the hands, feet, ankles, or lower legs, skin rash, itching. Precautions Ibuprofen is associated with several suspected or probable interactions that can affect the action of other drugs. Ibuprofen may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When ibuprofen is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to aminoglycoside-related side effects. Individuals taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid ibuprofen because ibuprofen also thins the blood, and excessive blood thinning may lead to bleeding. There are no adequate studies of ibuprofen in pregnant women. Therefore, ibuprofen is not recommended during pregnancy. Most NSAIDs are excreted in breast milk. In general, mothers who breast feed should avoid the use of NSAIDs because of possible effects on the fetus.