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Details Nevimune (Generic Viramune) Generic Name: Nevirapine Packet of 10 x 200 mg Tablets Manufactured by Cipla Description Nevirapine is a non-nucleoside reverse transcriptase inhibitor with activity against HIV-1. Nevirapine binds directly to reverse transcriptase and blocks the RNA-dependent and DNA dependent DNA polymerase activities by causing a disruption of the enzyme's catalytic site. The HIV-2 reverse transcriptase and human DNA polymerases (such as DNA polymerases a, b, g or d ) are not inhibited by nevirapine. Indications Nevimune is indicated for use in combination with other antiretroviral agents for the treatment of HIV-1 infection. Resistant virus emerges rapidly and uniformly when nevirapine is administered as monotherapy. Therefore, nevirapine should always be administered in combination with at least one additional antiretroviral agent. Further Information For further information, see Cipla's information page on Nevimune.