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Details Rheumacin SR(Indocin) Generic Name: Indomethacin Packets of 100 x 75 mg Capsules Manufactured by Pacific Pharmaceuticals Use Rheumacin is used to relieve the inflammation, swelling, stiffness and joint pain associated with moderate or severe rheumatoid arthritis and osteoarthritis (the most common form of arthritis), and ankylosing spondylitis (arthritis of the spine). It is also used to treat bursitis, tendinitis (acute painful shoulder), acute gouty arthritis, and other kinds of pain. Dosage Rheumacin (Indocin) should be taken with food or an antacid, and with a full glass of water. Never take on an empty stomach. Take this medication exactly as prescribed by your doctor. If you are using Rheumacin (Indocin) for arthritis, it should be taken regularly. Do not lie down for about 20 to 30 minutes after taking Rheumacin (Indocin). This helps prevent irritation that could lead to trouble in swallowing. Side effects More common side effects may include: abdominal pain, constipation, depression, diarrhea, dizziness, fatigue, headache, heartburn, indigestion, nausea, ringing in the ears, sleepiness or excessive drowsiness, stomach pain, stomach upset, vertigo, vomiting. Less common or rare side effects may include: anemia, anxiety, asthma, behavior disturbances, bloating, blurred vision, breast changes, changes in heart rate, chest pain, coma, congestive heart failure, convulsions, decrease in white blood cells, fever, fluid in lungs, fluid retention, flushing, gas, hair loss, hepatitis, high or low blood pressure, hives, itching, increase in blood sugar, insomnia, kidney failure, labored breathing, light-headedness, loss of appetite, mental confusion, muscle weakness, nosebleed, peptic ulcer, problems in hearing, rash, rectal bleeding, Stevens-Johnson syndrome (skin peeling), stomach or intestinal bleeding, sweating, twitching, unusual redness of skin, vaginal bleeding, weight gain, worsening of epilepsy, yellow eyes and skin Precautions Rheumacin (Indocin) prolongs bleeding time. If you are taking blood-thinning medication, this drug should be taken with caution. Your doctor should prescribe the lowest possible effective dose. The incidence of side effects increases as dosage increases. Peptic ulcers and bleeding can occur without warning, especially in people over 65. This drug should be used with caution if you have kidney or liver disease, and it can cause liver inflammation in some people. Do not take aspirin or any other anti-inflammatory medications while taking Rheumacin (Indocin), unless your doctor tells you to do so. If you have heart disease or high blood pressure, this drug can increase water retention. This drug can mask the symptoms of an existing infection. Rheumacin (Indocin) may cause you to become drowsy or less alert; therefore, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended. Rheumacin (Indocin) may also cause confusion and, rarely, psychosis, especially in older adults.