Selgin (Selegiline) - 5mg (10 Tablets)
| Main Use |
Active Integredient |
Marketed Name |
| Parkinson's disease |
Selegiline |
SelginĀ® |
Uses
Selgin (Selegiline) is used to help control the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) in people who are taking levodopa and carbidopa combination (Sinemet). Selegiline may help people with Parkinson's disease by decreasing the dose of levodopa/carbidopa needed to control symptoms, stopping the effects of levodopa/carbidopa from wearing off between doses, and increasing the length of time that levodopa/carbidopa will continue to control symptoms.
Selegiline is in a group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.
Dosage and administration
Selgin (Selegiline) tablets should be taken orally. Patients may be directed to take this medication twice daily. In order to avoid difficulty sleeping, patients are often directed to take this medication at breakfast and lunchtime. The standard maximum dosage is 5mg twice per day.
Patients should always consult their physician before taking this drug, and never exceed the dosage prescribed to them. If your physician has directed you to take this drug together with another drug to treat Parkinson's disease, such as levodopa, you may be instructed to decrease your dosage of levodopa after you have been taking selegiline for 2 to 3 days.
Patients should be aware that it may take a few weeks for the full effects and benefits of this drug to be noticed. You should never discontinue taking this drug unless you have been directed to do so by your physician.
Side effects
This medication may cause stomach upset, loss of appetite, nausea, heartburn or dry mouth. These effects should subside as your body adjusts to the medication. If they continue or become bothersome, inform your physician. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use saliva substitute. Infrequently, this medication may increase the skin's sensitivity to sunlight. If this happens to you, avoid prolonged sun exposure, wear protective clothing and use a sunscreen. Avoid sunlamps. This medication can cause dizziness and lightheadedness especially during the first few days of therapy. Avoid tasks requiring alertness if you experience these effects. Notify your physician promptly if you develop any of the following side effects: severe headache, chest pain, irregular heartbeat, tremors, clumsiness, confusion, involuntary movements (especially of the hands or face), nightmares, hallucinations, difficulty breathing, difficulty urinating. If you notice other effects not listed above, contact your physician or pharmacist.
Precautions
This drug should not be used with the following medications because very serious interactions may occur: apraclonidine, brimonidine, bethanidine, bupropion, buspirone, carbamazepine, dextromethorphan, entacapone, herbal products (e.g., ma huang), indoramin, meperidine, papaverine, sibutramine, SSRI antidepressants (e.g., fluoxetine, citalopram), sympathomimetics (e.g., methylphenidate, ephedrine), tolcapone, tricyclic antidepressants (e.g., amitriptyline, doxepin), "triptans" (e.g., sumatriptan, zolmitriptan).
If you are currently using any of these medications, tell your physician or pharmacist before starting selegiline. Before using this medication, be sure to tell your physician what medicines (both prescription and nonprescription) you are taking, including: levodopa, insulin and oral antidiabetic drugs, other MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine), tryptophan, sedatives and drugs used to aid sleep, drugs used for blood pressure.
Consult your physician about the need to watch your intake of foods containing tyramine. It is possible consuming tyramine- containing foods while using this medication could cause headache and/or increased blood pressure and could lead to a medical emergency. Tyramine food precautions should be observed for at least 2 weeks after you stop using this medication. The following is a partial list of tyramine-containing foods: Meat or Fish - pickled herring/liver/dry sausage/salami/meats prepared with tenderizer; Dairy - yogurt/sour cream/aged cheeses (cream or cottage cheese are okay); Beverages - beer/red wine/sherry - Avoid excessive amount of caffeine-containing colas/coffee/tea; Fruits and Vegetables - avocado/bananas/figs/raisins/broad beans/sauerkraut; Other - yeast extract/soy sauce/large amounts of chocolate. Do not start or stop any medicine without physician or pharmacist approval. Delivery Time: 7-14 Days
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